Show simple item record

High-provitamin A carotenoid (orange) maize increases hepatic vitamin A reserves of offspring in a vitamin A-depleted sow-piglet model during lactation 1–4

Author: Heying, E.K.
Author: Grahn, M.
Author: Pixley, K.V.
Author: Rocheford, T.
Author: Tanumihardjo, S.A.
Year: 2013
URI: http://hdl.handle.net/10883/18625
Descriptors: Retinol
Descriptors: Carotenoids
Descriptors: Maize
Descriptors: Provitamin
Abstract: The relationship of dietary vitamin A transfer from mother to fetus is not well understood. The difference in swine offspring liver reserves was investigated between single-dose vitamin A provided to the mother post-conception compared with continuous provitamin A carotenoid dietary intake from biofortified (enhanced provitamin A) orange maize (OM) fed during gestation and lactation. Vitamin A-depleted sows were fed OM (n = 5) or white maize (WM) + 1.05 mmol retinyl palmitate administered at the beginning of gestation (n = 6). Piglets (n = 102) were killed at 0, 10, 20, and 28 d after birth. Piglets from sows fed OM had higher liver retinol reserves (P < 0.0001) and a combined mean concentration from d 10 to 28 of 0.11 ± 0.030 μmol/g. Piglets from sows fed WM had higher serum retinol concentrations (0.56 ± 0.25 μmol/L; P = 0.0098) despite lower liver retinol concentrations of 0.068 ± 0.026 μmol/g from d 10 to 28. Milk was collected at 0, 5, 10, 20, and 28 d. Sows fed OM had a higher milk retinol concentration (1.36 ± 1.30 μmol/L; P = 0.038), than those fed WM (0.93 ±1.03 μmol/L). Sow livers were collected at the end of the study (n = 3/group) and had identical retinol concentrations (0.22 ± 0.05 μmol/g). Consumption of daily provitamin A carotenoids by sows during gestation and lactation increased liver retinol status in weanling piglets, illustrating the potential for provitamin A carotenoid consumption from biofortified staple foods to improve vitamin A reserves. Biofortified OM could have a measurable impact on vitamin A status in deficient populations if widely adopted.
Language: English
Publisher: American Society for Nutrition
Copyright: CIMMYT manages Intellectual Assets as International Public Goods. The user is free to download, print, store and share this work. In case you want to translate or create any other derivative work and share or distribute such translation/derivative work, please contact CIMMYT-Knowledge-Center@cgiar.org indicating the work you want to use and the kind of use you intend; CIMMYT will contact you with the suitable license for that purpose.
Type: Article
Place: USA
Pages: 1141-1146
Journal issue: 7
Journal: The Journal of Nutrition
Journal volume: 143
DOI: 10.3945/jn.113.175679


Files in this item

Thumbnail

This item appears in the following Collection(s)

  • Genetic Resources
    Genetic Resources including germplasm collections, wild relatives, genotyping, genomics, and IP

Show simple item record