| Creator:
| Rashid, Z. |
| Creator:
| Sofi, M. |
| Creator:
| Harlapur, S.I. |
| Creator:
| Kachapur, R.M. |
| Creator:
| Dar, Z.A. |
| Creator:
| Singh, P.K. |
| Creator:
| Zaidi, P.H. |
| Creator:
| Vivek, B. |
| Creator:
| Nair, S.K. |
| Year:
| 2020 |
| URI:
| https://hdl.handle.net/10883/21137 |
| Language:
| English |
| Publisher:
| Nature Publishing Group |
| Copyright:
| CIMMYT manages Intellectual Assets as International Public Goods. The user is free to download, print, store and share this work. In case you want to translate or create any other derivative work and share or distribute such translation/derivative work, please contact CIMMYT-Knowledge-Center@cgiar.org indicating the work you want to use and the kind of use you intend; CIMMYT will contact you with the suitable license for that purpose |
| Type:
| Article |
| Place of Publication:
| London (United Kingdom) |
| Volume:
| 10 |
| DOI:
| 10.1038/s41598-020-78928-5 |
| Description:
| Northern Corn Leaf Blight (NCLB) caused by Setosphaeria turcica, is one of the most important diseases of maize world-wide, and one of the major reasons behind yield losses in maize crop in Asia. In the present investigation, a high-resolution genome wide association study (GWAS) was conducted for NCLB resistance in three association mapping panels, predominantly consisting of tropical lines adapted to different agro-ecologies. These panels were phenotyped for disease severity across three locations with high disease prevalence in India. High density SNPs from Genotyping-by-sequencing were used in GWAS, after controlling for population structure and kinship matrices, based on single locus mixed linear model (MLM). Twenty-two SNPs were identified, that revealed a significant association with NCLB in the three mapping panels. Haplotype regression analysis revealed association of 17 significant haplotypes at FDR ≤ 0.05, with two common haplotypes across three maize panels. Several of the significantly associated SNPs/haplotypes were found to be co-located in chromosomal bins previously reported for major genes like Ht2, Ht3 and Htn1 and QTL for NCLB resistance and multiple foliar disease resistance. Phenotypic variance explained by these significant SNPs/haplotypes ranged from low to moderate, suggesting a breeding strategy of combining multiple resistance alleles towards resistance for NCLB. |
| Agrovoc:
| MAIZE |
| Agrovoc:
| DISEASE RESISTANCE |
| Agrovoc:
| GENETICS |
| Agrovoc:
| BLIGHT |
| Related Datasets:
| https://www.nature.com/articles/s41598-020-78928-5#Sec26 |
| ISSN:
| 2045-2322 |
| Journal:
| Nature Scientific Reports |
| Article number:
| 21949 |
