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Linkage mapping and genome-wide association study reveals conservative QTL and candidate genes for Fusarium rot resistance in maize

Creator: Yabin Wu
Creator: Zijian Zhou
Creator: Chaopei Dong
Creator: Chen, J.
Creator: Junqiang Ding
Creator: Zhang, X.
Creator: Cong Mu
Creator: Yuna Chen
Creator: Xiaopeng Li
Creator: Huimin Li
Creator: Yanan Han
Creator: Ruixia Wang
Creator: Xiaodong Sun
Creator: Jingjing Li
Creator: Xiaodong Dai
Creator: Weibin Song
Creator: Wei Chen
Creator: Jianyu Wu
Year: 2020
Language: English
Publisher: BioMed Central
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Type: Article
Place of Publication: London (United Kingdom)
Volume: 21
DOI: 10.1186/s12864-020-6733-7
Keywords: Ear Rot
Keywords: Genome-Wide Association Study
Keywords: Candidate Genes
Description: Background. Fusarium ear rot (FER) caused by Fusarium verticillioides is a major disease of maize that reduces grain yield and quality globally. However, there have been few reports of major loci for FER were verified and cloned. Result. To gain a comprehensive understanding of the genetic basis of natural variation in FER resistance, a recombinant inbred lines (RIL) population and one panel of inbred lines were used to map quantitative trait loci (QTL) for resistance. As a result, a total of 10 QTL were identified by linkage mapping under four environments, which were located on six chromosomes and explained 1.0–7.1% of the phenotypic variation. Epistatic mapping detected four pairs of QTL that showed significant epistasis effects, explaining 2.1–3.0% of the phenotypic variation. Additionally, 18 single nucleotide polymorphisms (SNPs) were identified across the whole genome by genome-wide association study (GWAS) under five environments. Compared linkage and association mapping revealed five common intervals located on chromosomes 3, 4, and 5 associated with FER resistance, four of which were verified in different near-isogenic lines (NILs) populations. GWAS identified three candidate genes in these consistent intervals, which belonged to the Glutaredoxin protein family, actin-depolymerizing factors (ADFs), and AMP-binding proteins. In addition, two verified FER QTL regions were found consistent with Fusarium cob rot (FCR) and Fusarium seed rot (FSR). Conclusions. These results revealed that multi pathways were involved in FER resistance, which was a complex trait that was controlled by multiple genes with minor effects, and provided important QTL and genes, which could be used in molecular breeding for resistance.
Agrovoc: MAIZE
Agrovoc: ROTS
Agrovoc: GENES
Related Datasets:
ISSN: 1471-2164
Journal: BMC Genomics
Article number: 357

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  • Maize
    Maize breeding, phytopathology, entomology, physiology, quality, and biotech

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