Show simple item record

Independent introductions and admixtures have contributed to adaptation of European maize and its American counterparts

Author: Brandenburg, J.T.
Author: Tristan Mary-Huard
Author: Rigaill, G.
Author: Hearne, S.
Author: Corti, H.
Author: Joets, J.
Author: Vitte, C.
Author: Charcosset, A.
Author: Nicolas, S.D.
Author: Tenaillon, M.I.
Year: 2017
URI: http://hdl.handle.net/10883/18268
Abstract: Through the local selection of landraces, humans have guided the adaptation of crops to a vast range of climatic and ecological conditions. This is particularly true of maize, which was domesticated in a restricted area of Mexico but now displays one of the broadest cultivated ranges worldwide. Here, we sequenced 67 genomes with an average sequencing depth of 18x to document routes of introduction, admixture and selective history of European maize and its American counterparts. To avoid the confounding effects of recent breeding, we targeted germplasm (lines) directly derived from landraces. Among our lines, we discovered 22,294,769 SNPs and between 0.9% to 4.1% residual heterozygosity. Using a segmentation method, we identified 6,978 segments of unexpectedly high rate of heterozygosity. These segments point to genes potentially involved in inbreeding depression, and to a lesser extent to the presence of structural variants. Genetic structuring and inferences of historical splits revealed 5 genetic groups and two independent European introductions, with modest bottleneck signatures. Our results further revealed admixtures between distinct sources that have contributed to the establishment of 3 groups at intermediate latitudes in North America and Europe. We combined differentiation- and diversity-based statistics to identify both genes and gene networks displaying strong signals of selection. These include genes/gene networks involved in flowering time, drought and cold tolerance, plant defense and starch properties. Overall, our results provide novel insights into the evolutionary history of European maize and highlight a major role of admixture in environmental adaptation, paralleling recent findings in humans.
Format: PDF
Language: English
Publisher: Public Library of Science
Copyright: CIMMYT manages Intellectual Assets as International Public Goods. The user is free to download, print, store and share this work. In case you want to translate or create any other derivative work and share or distribute such translation/derivative work, please contact CIMMYT-Knowledge-Center@cgiar.org indicating the work you want to use and the kind of use you intend; CIMMYT will contact you with the suitable license for that purpose.
Type: Article
Place of Publication: San Francisco, USA
Pages: e1006666
Issue: 3
Volume: 13
DOI: 10.1371/journal.pgen.1006666
Country of Focus: MEXICO
Country of Focus: NORTH AMERICA
Agrovoc: MAIZE
Agrovoc: GERMPLASM
Agrovoc: INTRODUCED BREEDS
Agrovoc: ADAPTATION
Related Datasets: https://ndownloader.figshare.com/articles/4758772/versions/1
Journal: PLoS Genetics


Files in this item

Thumbnail

This item appears in the following Collection(s)

  • Genetic Resources
    Genetic Resources including germplasm collections, wild relatives, genotyping, genomics, and IP

Show simple item record