In order to meet future wheat demand it is necessary to increase yield potential and develop stress adapted genotypes. To do so, research and breeding is conducted at CIMMYT through the International Wheat Yield Partnership (IWYP) platform combining physiology, genetics, and breeding. Physiological breeding focuses on understanding the physiology and genetics of key traits and conducting complementary crosses among them based on conceptual models to utilize the diversity present in the CIMMYT germplasm. Physiological breeding combined with genetic approaches (GWAS, QTLs, Genomic Selection) are used in the program to achieve genetic gains. (Reynolds and Langridge 2016 Current opinion in plant biology).