Type
Date
Corporate author
Editor
Illustrator
Producer
Photographer
Contributor
Writer
Translator
Journal Title
Journal ISSN
Volume Title
Access Rights
APA citation
Dwivedi, S., Garcia Oliveira, A. L., Govindaraj, M., & Ortiz, R. (2023). Biofortification to avoid malnutrition in humans in a changing climate: Enhancing micronutrient bioavailability in seed, tuber, and storage roots. Frontiers in Plant Science, 14, 1119148. https://doi.org/10.3389/fpls.2023.1119148
ISO citation
Abstract
Description
Malnutrition results in enormous socio-economic costs to the individual, their community, and the nation’s economy. The evidence suggests an overall negative impact of climate change on the agricultural productivity and nutritional quality of food crops. Producing more food with better nutritional quality, which is feasible, should be prioritized in crop improvement programs. Biofortification refers to developing micronutrient -dense cultivars through crossbreeding or genetic engineering. This review provides updates on nutrient acquisition, transport, and storage in plant organs; the cross-talk between macro- and micronutrients transport and signaling; nutrient profiling and spatial and temporal distribution; the putative and functionally characterized genes/single-nucleotide polymorphisms associated with Fe, Zn, and β-carotene; and global efforts to breed nutrient-dense crops and map adoption of such crops globally. This article also includes an overview on the bioavailability, bioaccessibility, and bioactivity of nutrients as well as the molecular basis of nutrient transport and absorption in human. Over 400 minerals (Fe, Zn) and provitamin A-rich cultivars have been released in the Global South. Approximately 4.6 million households currently cultivate Zn-rich rice and wheat, while ~3 million households in sub-Saharan Africa and Latin America benefit from Fe-rich beans, and 2.6 million people in sub-Saharan Africa and Brazil eat provitamin A-rich cassava. Furthermore, nutrient profiles can be improved through genetic engineering in an agronomically acceptable genetic background. The development of “Golden Rice” and provitamin A-rich dessert bananas and subsequent transfer of this trait into locally adapted cultivars are evident, with no significant change in nutritional profile, except for the trait incorporated. A greater understanding of nutrient transport and absorption may lead to the development of diet therapy for the betterment of human health.
Keywords
Citation
Copyright
CIMMYT manages Intellectual Assets as International Public Goods. The user is free to download, print, store and share this work. In case you want to translate or create any other derivative work and share or distribute such translation/derivative work, please contact CIMMYT-Knowledge-Center@cgiar.org indicating the work you want to use and the kind of use you intend; CIMMYT will contact you with the suitable license for that purpose
Journal
Frontiers in Plant Science
Journal volume
14
Journal issue
Article number
1119148
Place of Publication
Switzerland
Publisher
Frontiers
Related Datasets
CGIAR Initiatives
Initiative
Breeding Resources
Impact Area
Climate adaptation & mitigation
Environmental health & biodiversity
Nutrition, health & food security
Poverty reduction, livelihoods & jobs
Environmental health & biodiversity
Nutrition, health & food security
Poverty reduction, livelihoods & jobs
Action Area
Systems Transformation
Resilient Agrifood Systems
Genetic Innovation
Resilient Agrifood Systems
Genetic Innovation
Donor or Funder
CGIAR Trust Fund