Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement

Gaurav, K.; Sanu Arora; Silva, P.; Sánchez-Martín, J.; Horsnell, R.; Liangliang Gao; Brar, G.S.; Widrig, V.; Raupp, W.J.; Singh, N.; Shuangye Wu; Kale, S.; Chinoy, C.; Nicholson, P.; Quiroz-Chávez, J.; Simmonds, J.; Hayta, S.; Smedley, M.A.; Harwood, W.; Pearce, S.; Gilbert, D.; Ngonidzashe Kangara; Gardener, C.; Forner-Martínez, M.; Jiaqian Liu; Guotai Yu; Boden, S.A.; Pascucci, A.; Ghosh, S.; Hafeez, A.N.; O’Hara, T.; Waites, J.; Cheema, J.; Steuernagel, B.; Patpour, M.; Justesen, A.F.; Shuyu Liu; Rudd, J.C.; Avni, R.; Sharon, A.; Steiner, B.; Kirana, R.P.; Buerstmayr, H.; Mehrabi, A.A.; Nasyrova, F.Y.; Chayut, N.; Matny, O.; Steffenson, B.; Sandhu, N.; Chhuneja, P.; Lagudah, E.; Elkot, A.F.; Tyrrell, S.; Xingdong Bian; Davey, R.; Simonsen, M.; Schauser, L.; Tiwari, V.K.; Kutcher, H.R.; Hucl, P.J.; Aili Li; Liu Dengcai; Long Mao; Xu, S.; Brown-Guedira, G.; Faris, J.; Dvorak, J.; Ming-Cheng Luo; Krasileva, K.; Lux, T.; Artmeier, S.; Mayer, K.; Uauy, C.; Mascher, M.; Bentley, A.R.; Keller, B.; Poland, J.; Wulff, B.B.H.

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Gaurav, K., Arora, S., Silva, P., Sánchez‐Martín, J., Horsnell, R., Gao, L., Brar, G. S., Widrig, V., Raupp, W. J., Singh, N., Wu, S., Kale, S. M., Chinoy, C., Nicholson, P., Quiroz-Chávez, J., Simmonds, J., Hayta, Ş., Smedley, M., Harwood, W., . . . Wulff, B. B. H. (2021). Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement. Nature Biotechnology, 40(3), 422–431. https://doi.org/10.1038/s41587-021-01058-4

Description

Aegilops tauschii, the diploid wild progenitor of the D subgenome of bread wheat, is a reservoir of genetic diversity for improving bread wheat performance and environmental resilience. Here we sequenced 242 Ae. tauschii accessions and compared them to the wheat D subgenome to characterize genomic diversity. We found that a rare lineage of Ae. tauschii geographically restricted to present-day Georgia contributed to the wheat D subgenome in the independent hybridizations that gave rise to modern bread wheat. Through k-mer-based association mapping, we identified discrete genomic regions with candidate genes for disease and pest resistance and demonstrated their functional transfer into wheat by transgenesis and wide crossing, including the generation of a library of hexaploids incorporating diverse Ae. tauschii genomes. Exploiting the genomic diversity of the Ae. tauschii ancestral diploid genome permits rapid trait discovery and functional genetic validation in a hexaploid background amenable to breeding.

URI

https://hdl.handle.net/10883/21731

Copyright

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Journal

Nature Biotechnology

Journal volume

40

Journal issue

3

Place of Publication

United Kingdom

Publisher

Nature Publishing Group

DOI

https://doi.org/10.1038/s41587-021-01058-4

AGROVOC

POPULATION GENETICS; AEGILOPS; PLANT BREEDING; CROP IMPROVEMENT; SOFT WHEAT

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CGIAR Initiatives

Initiative

Accelerated Breeding

Impact Area

Nutrition, health & food security

Action Area

Genetic Innovation

CGSpace URL

https://hdl.handle.net/10568/126588

Collections

Wheat

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