Person:
Sehgal, D.

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Sehgal
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Sehgal, D.

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Now showing 1 - 8 of 8
  • Capturing wheat phenotypes at the genome level
    (Frontiers Media S.A., 2022) Hussain, B.; Akpınar, B.A.; Alaux, M.; Algharib, A.M.; Sehgal, D.; Ali, Z.; Aradottir, G.I.; Batley, J.; Bellec, A.; Bentley, A.R.; Cagirici, H.B.; Cattivelli, L.; Choulet, F.; Cockram, J.; Desiderio, F.; Devaux, P.; Dogramaci, M.; Dorado, G.; Dreisigacker, S.; Edwards, D.; El Hassouni, K.; Eversole, K.; Fahima, T.; Figueroa, M.; Gálvez, S.; Gill, K.S.; Govta, L.; Gul, A.; Hensel, G.; Hernandez, P.; Crespo Herrera, L.A.; Ibrahim, A.M.H.; Kilian, B.; Korzun, V.; Krugman, T.; Yinghui Li; Shuyu Liu; Mahmoud, A.F.; Morgounov, A.; Muslu, T.; Naseer, F.; Ordon, F.; Paux, E.; Perovic, D.; Reddy, G.V.P.; Reif, J.C.; Reynolds, M.P.; Roychowdhury, R.; Rudd, J.C.; Sen, T.Z.; Sukumaran, S.; Bahar Sogutmaz Ozdemir; Tiwari, V.K.; Ullah, N.; Unver, T.; Yazar, S.; Appels, R.; Budak, H.
    Publication
  • Editorial: genetics and genomics to enhance crop production, towards food security
    (Frontiers, 2021) Kumar, A.; Mir, R.; Sehgal, D.; Agarwal, P.; Carter, A.
    Publication
  • Wheat genomics and breeding: bridging the gap
    (CABI, 2021) Hussain, B.; Akpınar, B.A.; Alaux, M.; Algharib, A.M.; Sehgal, D.; Ali, Z.; Appels, R.; Aradottir, G.I.; Batley, J.; Bellec, A.; Bentley, A.R.; Cagirici, H.B.; Cattivelli, L.; Choulet, F.; Cockram, J.; Desiderio, F.; Devaux, P.; Dogramaci, M.; Dorado, G.; Dreisigacker, S.; Edwards, D.; El Hassouni, K.; Eversole, K.; Fahima, T.; Figueroa, M.; Gálvez, S.; Gill, K.S.; Govta, L.; Gul, A.; Hensel, G.; Hernandez, P.; Crespo Herrera, L.A.; Ibrahim, A.M.H.; Kilian, B.; Korzun, V.; Krugman, T.; Yinghui Li; Shuyu Liu; Mahmoud, A.F.; Morgounov, A.; Muslu, T.; Naseer, F.; Ordon, F.; Paux, E.; Perovic, D.; Reddy, G.V.P.; Reif, J.C.; Reynolds, M.P.; Roychowdhury, R.; Rudd, J.C.; Sen, T.Z.; Sukumaran, S.; Tiwari, V.K.; Ullah, N.; Unver, T.; Yazar, S.; Budak, H.
    Publication
  • GWAS to identify genetic loci for resistance to yellow rust in wheat pre-breeding lines derived from diverse exotic crosses
    (Frontiers, 2019) Ledesma-Ramirez, L.; Solís Moya, E.; Iturriaga, G.; Sehgal, D.; Reyes-Valdés, M.H.; Montero-Tavera, V.; Sansaloni, C.; Burgueño, J.; Ortiz, C.; Aguirre-Mancilla, C.L.; Ramirez-Pimentel, J.G.; Vikram, P.; Singh, S.
    Publication
  • Identification of novel quantitative trait loci linked to crown rot resistance in spring wheat
    (MDPI, 2018) Erginbas Orakci, G.; Sehgal, D.; Sohail, Q.; Ogbonnaya, F.C.; Dreisigacker, S.; Pariyar, S.R.; Dababat, A.A.
    Crown rot (CR), caused by various Fusarium species, is a major disease in many cereal-growing regions worldwide. Fusarium culmorum is one of the most important species, which can cause significant yield losses in wheat. A set of 126 advanced International Maize and Wheat Improvement Center (CIMMYT) spring bread wheat lines were phenotyped against CR for field crown, greenhouse crown and stem, and growth room crown resistance scores. Of these, 107 lines were genotyped using Diversity Array Technology (DArT) markers to identify quantitative trait loci linked to CR resistance by genome-wide association study. Results of the population structure analysis grouped the accessions into three sub-groups. Genome wide linkage disequilibrium was large and declined on average within 20 cM (centi-Morgan) in the panel. General linear model (GLM), mixed linear model (MLM), and naïve models were tested for each CR score and the best model was selected based on quarantine-quarantine plots. Three marker-trait associations (MTAs) were identified linked to CR resistance; two of these on chromosome 3B were associated with field crown scores, each explaining 11.4% of the phenotypic variation and the third MTA on chromosome 2D was associated with greenhouse stem score and explained 11.6% of the phenotypic variation. Together, these newly identified loci provide opportunity for wheat breeders to exploit in enhancing CR resistance via marker-assisted selection or deployment in genomic selection in wheat breeding programs.
    Publication
  • Mining centuries old In situ conserved turkish wheat landraces for grain yield and stripe rust resistance genes
    (Frontiers, 2016) Sehgal, D.; Dreisigacker, S.; Belen, S.; Kucukozdemir, U.; Mert, Z.; Ozer, E.; Morgounov, A.
    Wheat landraces in Turkey are an important genetic resource for wheat improvement. An exhaustive 5-year (2009–2014) effort made by the International Winter Wheat Improvement Programme (IWWIP), a cooperative program between the Ministry of Food, Agriculture and Livestock of Turkey, the International Center for Maize and Wheat Improvement (CIMMYT) and the International Center for Agricultural Research in the Dry Areas (ICARDA), led to the collection and documentation of around 2000 landrace populations from 55 provinces throughout Turkey. This study reports the genetic characterization of a subset of bread wheat landraces collected in 2010 from 11 diverse provinces using genotyping-by-sequencing (GBS) technology. The potential of this collection to identify loci determining grain yield and stripe rust resistance via genome-wide association (GWA) analysis was explored. A high genetic diversity (diversity index = 0.260) and a moderate population structure based on highly inherited spike traits was revealed in the panel. The linkage disequilibrium decayed at 10 cM across the whole genome and was slower as compared to other landrace collections. In addition to previously reported QTL, GWA analysis also identified new candidate genomic regions for stripe rust resistance, grain yield, and spike productivity components. New candidate genomic regions reflect the potential of this landrace collection to further increase genetic diversity in elite germplasm.
    Publication
  • Identification of genomic associations for adult plant resistance in the background of popular South Asian wheat cultivar, PBW343
    (Frontiers, 2016) Huihui Li; Singh, S.; Bhavani, S.; Singh, R.P.; Sehgal, D.; Basnet, B.R.; Vikram, P.; Burgueño, J.; Huerta-Espino, J.
    Rusts, a fungal disease as old as its host plant wheat, has caused havoc for over 8000 years. As the rust pathogens can evolve into new virulent races which quickly defeat the resistance that primarily rely on race specificity, adult plant resistance (APR) has often been found to be race non-specific and hence is considered to be a more reliable and durable strategy to combat this malady. Over decades sets of donor lines have been identified at International Maize and Wheat Improvement Center (CIMMYT) representing a wide range of APR sources in wheat. In this study, using nine donors and a common parent “PBW343,” a popular Green Revolution variety at CIMMYT, the nested association mapping (NAM) population of 1122 lines was constructed to understand the APR genetics underlying these founder lines. Thirty-four QTL were associated with APR to rusts, and 20 of 34 QTL had pleiotropic effects on SR, YR and LR resistance. Three chromosomal regions, associated with known APR genes (Sr58/Yr29/Lr46, Sr2/Yr30/Lr27, and Sr57/Yr18/Lr34), were also identified, and 13 previously reported QTL regions were validated. Of the 18 QTL first detected in this study, 7 were pleiotropic QTL, distributing on chromosomes 3A, 3B, 6B, 3D, and 6D. The present investigation revealed the genetic relationship of historical APR donor lines, the novel knowledge on APR, as well as the new analytical methodologies to facilitate the applications of NAM design in crop genetics. Results shown in this study will aid the parental selection for hybridization in wheat breeding, and envision the future rust management breeding for addressing potential threat to wheat production and food security.
    Publication
  • A high density GBS map of bread wheat and its application for dissecting complex disease resistance traits
    (BioMed Central, 2015) Huihui Li; Vikram, P.; Singh, R.P.; Kilian, A.; Carling, J.; Jie Song; Burgueño, J.; Bhavani, S.; Huerta-Espino, J.; Payne, T.S.; Sehgal, D.; Wenzl, P.; Singh, S.
    Genotyping-by-sequencing (GBS) is a high-throughput genotyping approach that is starting to be used in several crop species, including bread wheat. Anchoring GBS tags on chromosomes is an important step towards utilizing them for wheat genetic improvement. Here we use genetic linkage mapping to construct a consensus map containing 28644 GBS markers. Results: Three RIL populations, PBW343 × Kingbird, PBW343 × Kenya Swara and PBW343 × Muu, which share a common parent, were used to minimize the impact of potential structural genomic variation on consensus-map quality. The consensus map comprised 3757 unique positions, and the average marker distance was 0.88 cM, obtained by calculating the average distance between two adjacent unique positions. Significant variation of segregation distortion was observed across the three populations. The consensus map was validated by comparing positions of known rust resistance genes, and comparing them to wheat reference genome sequences recently published by the International Wheat Genome Sequencing Consortium, Rye and Ae. tauschii genomes. Three well-characterized rust resistance genes (Sr58/Lr46/Yr29, Sr2/Yr30/Lr27, and Sr57/Lr34/Yr18) and 15 published QTLs for wheat rusts were validated with high resolution. Fifty-two per cent of GBS tags on the consensus map were successfully aligned through BLAST to the right chromosomes on the wheat reference genome sequence. Conclusion: The consensus map should provide a useful basis for analyzing genome-wide variation of complex traits. The identified genes can then be explored as genetic markers to be used in genomic applications in wheat breeding.
    Publication