Person: Pixley, K.V.
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Pixley
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K.V.
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Pixley, K.V.
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0000-0003-4068-7436 41 results
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- Edited eukaryotic translation initiation factors confer resistance against maize lethal necrosis(Wiley-Blackwell Publishing Ltd., 2024) Zhengyu Wen; Fengzhong Lu; Jung, M.; Humbert, S.; Marshall, L.; Hastings, C.; Wu, E.; Jones, T.; Pacheco, M.; Martinez, I.; Mahabaleswara, S.L.; Beyene, Y.; Prasanna, B.M.; Pixley, K.V.; Dhugga, K.
Publication - Genetic variation among elite inbred lines suggests potential to breed for BNI-capacity in maize(Nature Publishing Group, 2023) Petroli, C.; Guntur Venkata Subbarao; Burgueño, J.; Tadashi Yoshihashi; Huihui Li; Franco, J.; Pixley, K.V.
Publication - Impact of CGIAR maize germplasm in Sub-Saharan Africa(Elsevier, 2023) Krishna, V.; Lantican, M.A.; Prasanna, B.M.; Pixley, K.V.; Abdoulaye, T.; Menkir, A.; Banziger, M.; Erenstein, O.
Publication - Maize Lethal Necrosis disease: review of molecular and genetic resistance mechanisms, socio-economic impacts, and mitigation strategies in sub-Saharan Africa(BioMed Central, 2022) Biswal, A.K.; Alakonya, A.; Mottaleb, K.A.; Hearne, S.; Sonder, K.; Molnar, T.L.; Jones, A.M.; Pixley, K.V.; Prasanna, B.M.
Publication - Genome editing for tolerance to maize lethal necrosis(KALRO, [2021]) Beyene, Y.; Dhugga, K.; Gowda, M.; Gichuki, S.T.; Mugo, S.N.; Karanja, J.; Murithi, A.; Ogugo, V.; Olsen, M.; Pixley, K.V.; Prasanna, B.M.; Suresh, L.M.; Wen, A.; Albertsen, M.; Allen, K.; Calahan, P.; Church, L.; DeLeon, A.; Farrell, J.; Federova, M.; Fengler, K.; Gaffney, J.; Greene, T.; Gutterson, N.; Habben, J.E.; Harkins, K.; Humbert, S.; Jetty, R.; Jones, T.; Jung, M.; Bailin Li; Limberger, E.; Llaca, V.; May, G.D.; Meeley, B.; Meyer, M.; Muller, M.; Owens, M.; Pitts, A.; Pundt, D.; Sanyal, A.; Schulze, J.M.; Simcox, K.; Snopek, K.; Thatcher, S.; Wilke, A.; Wu, E.; Deping Xu; Zastrow-Hayes, G.; Jones, M.; Stewart, L.R.
Publication - Use of genome editing technology to accelerate development of resistance to maize lethal necrosis disease(CIMMYT, 2021) Karanja, J.; Dhugga, K.; Mugo, S.N.; Jung, M.; Beyene, Y.; Olsen, M.; Zhengyu Wen; Gichuki, S.T.; Pixley, K.V.
Publication - Accelerated breeding to improve resistance against maize lethal necrosis (MLN)(CIMMYT, 2020) Dhugga, K.; Mugo, S.N.; Jung, M.; Beyene, Y.; Karanja, J.; Olsen, M.; Zhengyu Wen; Gichuki, S.T.; Pixley, K.V.
Publication - Impacts of CGIAR maize improvement in sub-Saharan Africa, 1995-2015(CIMMYT, 2021) Krishna, V.; Lantican, M.A.; Prasanna, B.M.; Pixley, K.V.; Abdoulaye, T.; Menkir, A.; Banziger, M.; Erenstein, O.
Publication - Conservation and use of Latin American maize diversity: pillar of nutrition security and cultural heritage of humanity(MDPI, 2021) Guzzon, F.; Arandia Rios, L.W.; Caviedes Cepeda, G.M.; Céspedes Polo, M.; Chávez-Cabrera, A.; Muriel Figueroa, J.; Medina Hoyos, A.E.; Jara Calvo, T.W.; Molnar, T.L.; Narro, L.A.; Narro León, T.P.; Mejía, S.; Ospina Rojas, J.G.; Vasquez-Carrillo, G.; Preciado-Ortiz, R.E.; Zambrano, J.L.; Palacios-Rojas, N.; Pixley, K.V.
Publication - Provitamin A carotenoids in grain reduce aflatoxin contamination of maize while combating vitamin A deficiency(Frontiers, 2019) Suwarno, W.B.; Hannok, P.; Palacios-Rojas, N.; Windham, G.L.; Crossa, J.; Pixley, K.V.Aflatoxin contamination of maize grain and products causes serious health problems for consumers worldwide, and especially in low- and middle-income countries where monitoring and safety standards are inconsistently implemented. Vitamin A deficiency (VAD) also compromises the health of millions of maize consumers in several regions of the world including large parts of sub-Saharan Africa. We investigated whether provitamin A (proVA) enriched maize can simultaneously contribute to alleviate both of these health concerns. We studied aflatoxin accumulation in grain of 120 maize hybrids formed by crossing 3 Aspergillus flavus resistant and three susceptible lines with 20 orange maize lines with low to high carotenoids concentrations. The hybrids were grown in replicated, artificially-inoculated field trials at five environments. Grain of hybrids with larger concentrations of beta-carotene (BC), beta-cryptoxanthin (BCX) and total proVA had significantly less aflatoxin contamination than hybrids with lower carotenoids concentrations. Aflatoxin contamination had negative genetic correlation with BCX (-0.28, p < 0.01), BC (-0.18, p < 0.05), and proVA (-0.23, p < 0.05). The relative ease of breeding for increased proVA carotenoid concentrations as compared to breeding for aflatoxin resistance in maize suggests using the former as a component of strategies to combat aflatoxin contamination problems for maize. Our findings indicate that proVA enriched maize can be particularly beneficial where the health burdens of exposure to aflatoxin and prevalence of VAD converge with high rates of maize consumption.
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